Egfr Inhibitors Erlotinib Hydrochloride / Erlotinib HCl CAS 183319-69-9

EGFR Inhibitors Erlotinib Hydrochloride / Erlotinib HCL CAS 183319-69-9
 
Product Name: Erlotinib hydrochloride
Synonyms: ERLOTINIB HCL;ERLOTINIB HCL SALT;ERLOTINIB HCL SALT :TARCEVA;Erlotinib, Hydrochloride Salt;N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva; N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine;[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine;Tarceva Hydrochloride See E625000
CAS: 183319-69-9
MF: C22H24ClN3O4
MW: 429.9



Erlotinib hydrochloride Overview

Erlotinib hydrochloride is hydrochloride of molecular targeted drug erlotinib. The US Food and Drug Administration (FDA) has approved erlotinib (Tarceva) in combination with gemcitabine for the first-line treatment of locally advanced and metastatic pancreatic cancer.
Small molecule compound erlotinib is a kind of receptor tyrosine kinase inhibitors. It can inhibit the phosphorylation reaction through competitively combined with the catalytic site of receptor tyrosine kinase tyrosine with the ATP, thus blocking the under proliferative signal transduction, and inhibiting the activity of tumor cell ligand-dependent HER-1/EGFR in order to inhibit tumor cell proliferation. Erlotinib is another tyrosine kinase inhibitor for treatment of NSCLC. The results of clinical trials showed that its main toxicity and side effect were dose-dependent skin rashes and diarrhea, other rare side effects were headache, nausea, vomiting and the like.


Erlotinib hydrochloride Uses

1. Erlotinib hydrochloride is a kind of small molecule epidermal growth receptor tyrosine kinase reversible inhibitor. It is mainly used for the second-line or third-line treatment of locally advanced or metastatic non-small cell lung cancer and for the treatment of pancreatic cancer.
2. HER-1/EGFR tyrosine kinase inhibitors.
Chemical Properties Off-White Solid
Usage Selective epidermal growth  receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic
Usage Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.
Usage Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.



COA:









How to proceed
 

1. Pinpoint what you need, specification, CAS No., assay, grade.

2. Ensure the discreet parcel and offer the suitable shipping method for reference.

3. The payment that you available for.

4. Shipped out until you paid 100% in advance.

5. Arrange the shipment according to your requirements.

6. Tracked the code when it is online.

Our Advantage:

1.We have stock so we can delivery quickly at the very day when receive the payment.

2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.

3.High quality guarenteed, once any problem is found, the package would be reshipped for you

4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.

5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.



Delivery Note:
•  Sent out in 24hours once payment comfirm.

•  Professional agent make sure our ship fastly and safety

• Offer your tracking number to you once we get it ,in order to facilitate you track the express


FAQ
1.How about parcel delivery success rate ?

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend?

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx. EGFR Inhibitors Erlotinib Hydrochloride / Erlotinib HCL CAS 183319-69-9
 
Product Name: Erlotinib hydrochloride
Synonyms: ERLOTINIB HCL;ERLOTINIB HCL SALT;ERLOTINIB HCL SALT :TARCEVA;Erlotinib, Hydrochloride Salt;N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva; N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine;[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine;Tarceva Hydrochloride See E625000
CAS: 183319-69-9
MF: C22H24ClN3O4
MW: 429.9



Erlotinib hydrochloride Overview

Erlotinib hydrochloride is hydrochloride of molecular targeted drug erlotinib. The US Food and Drug Administration (FDA) has approved erlotinib (Tarceva) in combination with gemcitabine for the first-line treatment of locally advanced and metastatic pancreatic cancer.
Small molecule compound erlotinib is a kind of receptor tyrosine kinase inhibitors. It can inhibit the phosphorylation reaction through competitively combined with the catalytic site of receptor tyrosine kinase tyrosine with the ATP, thus blocking the under proliferative signal transduction, and inhibiting the activity of tumor cell ligand-dependent HER-1/EGFR in order to inhibit tumor cell proliferation. Erlotinib is another tyrosine kinase inhibitor for treatment of NSCLC. The results of clinical trials showed that its main toxicity and side effect were dose-dependent skin rashes and diarrhea, other rare side effects were headache, nausea, vomiting and the like.


Erlotinib hydrochloride Uses

1. Erlotinib hydrochloride is a kind of small molecule epidermal growth receptor tyrosine kinase reversible inhibitor. It is mainly used for the second-line or third-line treatment of locally advanced or metastatic non-small cell lung cancer and for the treatment of pancreatic cancer.
2. HER-1/EGFR tyrosine kinase inhibitors.
Chemical Properties Off-White Solid
Usage Selective epidermal growth  receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic
Usage Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.
Usage Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.



COA:









How to proceed
 

1. Pinpoint what you need, specification, CAS No., assay, grade.

2. Ensure the discreet parcel and offer the suitable shipping method for reference.

3. The payment that you available for.

4. Shipped out until you paid 100% in advance.

5. Arrange the shipment according to your requirements.

6. Tracked the code when it is online.

Our Advantage:

1.We have stock so we can delivery quickly at the very day when receive the payment.

2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.

3.High quality guarenteed, once any problem is found, the package would be reshipped for you

4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.

5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.



Delivery Note:
•  Sent out in 24hours once payment comfirm.

•  Professional agent make sure our ship fastly and safety

• Offer your tracking number to you once we get it ,in order to facilitate you track the express


FAQ
1.How about parcel delivery success rate ?

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend?

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.

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