Many foods match each other. Once you eat two different foods together, you can even seriously threaten your life! And now a lot of grapefruit listed, there are many dead opponents!
Drug + grapefruit juice = poison? This is real!
Explained: The active ingredients such as furocoumarin, naringenin and bergamot contained in grapefruit can inhibit the activity of a metabolic enzyme in the human body, thereby affecting drug metabolism and excretion. This may cause the drug to accumulate in large amounts in the body, causing excessive drug efficacy, aggravating adverse reactions, and even causing poisoning.
At present, there are 85 kinds of drugs that can be used to confirm that they cannot be served with grapefruit juice. Most of them are commonly used drugs, such as cholesterol-lowering drugs, antibiotics, and calcium channel blockers for the treatment of hypertension. In addition, some anti-cancer drugs are also involved. Immunosuppressants taken by patients in drug and organ transplants.
Of the 85 drugs that can react with grapefruit juice, 43 can cause severe drug side effects, including sudden death, acute renal failure, respiratory failure, and gastrointestinal bleeding.
Drugs that cannot be served with grapefruit:
Antihypertensive drugs
Since grapefruit itself is rich in potassium, it has antihypertensive effect, plus it can also increase the blood drug concentration of antihypertensive drugs. Therefore, eating grapefruit or drinking grapefruit juice during antihypertensive drugs is equivalent to increasing the drug. The amount may cause a sudden drop in blood pressure, and it may cause dizziness, palpitation, and weakness, and in severe cases it may induce angina, myocardial infarction, or stroke.
Lipid-lowering drugs
Lipid-lowering statins, such as simvastatin, atorvastatin, and lovastatin, are safer when prescribed. However, if you eat a lot of grapefruit or grapefruit juice while taking these medicines, the medicine will accumulate in the body, increasing the risk of adverse reactions such as liver damage, rhabdomyolysis, and even causing acute renal failure. In February 2005, the relevant British authorities again issued a warning that patients taking lipid-lowering drugs should not eat grapefruit or drink grapefruit juice during their medication.
Hypnotics
Grapefruit will delay the metabolism of sedative hypnotics such as diazepam (sedation) and midazolam, prolong the duration of drug action, and increase the symptoms of dizziness and drowsiness. On the second day of medication, there may be symptoms of “hangover†(such as dizziness, etc.). Attention should be paid especially to the use of medications such as high-altitude workers and drivers.
Birth control pills
Grapefruit will hinder women's absorption and use of contraceptives. If you eat grapefruit during medication, it may cause contraceptive failure.
Antiallergic drugs
Grapefruit may induce adverse reactions such as anti-allergic drugs such as terfenadine, causing dizziness, heart palpitations, arrhythmia and other symptoms.
Is there any problem with eating peaks?
The U.S. Food and Drug Administration believes that eating grapefruit just a few hours before or after taking it may still pose a great danger. Therefore, when taking these medicines, it is best to completely avoid or minimize the intake of grapefruit juice or fresh grapefruit.
Involving more drugs, and the absorption of grapefruit juice, there will be individual differences, simple and crude approach is to take medicine when you still endure a forbearance, do not behave.
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