Release date: 2009-08-11
There are more than 200 million patients with various liver diseases in China. Liver fibrosis is an essential part of the development of various types of chronic liver disease to cirrhosis and liver cancer. It is worth noting that, recently, at the "Furui Liver Fibrosis Forum" held in Beijing, the results of "multi-center clinical validation of FibroScan Chinese hepatitis B patients" shared by the experts brought new hope for the diagnosis of liver fibrosis.
The results show that the FibroScan non-invasive detection system can accurately detect the degree of liver fibrosis, which can prevent more than 75% of patients from liver biopsy, and can greatly improve the detection rate of cirrhosis. It has high scientific and clinical value for the diagnosis and evaluation of hepatitis C, hepatitis B and other liver diseases in China and even in Asia.
Relevant information shows that there are about 93 million people carrying hepatitis B virus in China, about 30 million people with current infections, about 40 million people carrying hepatitis C virus, and about 120 million people with fatty liver. Liver disease not only brings great suffering to many patients and their families, but also imposes a heavy burden on society. According to statistics, more than 500,000 patients die of liver disease each year in China, and the medical expenses caused by liver diseases far exceed the 100 billion yuan mark.
Experts pointed out that liver fibrosis is an essential part of the development of various types of chronic liver disease to liver cirrhosis and liver cancer, and most liver diseases including hepatitis, fatty liver and alcoholic liver may cause liver fibrosis. Liver fibrosis can be delayed or even reversed. The world famous liver disease authority, Dr. Hans Popper of the United States once pointed out: "Who will prevent or delay the occurrence of liver fibrosis, who will cure most chronic liver diseases." How to detect and treat liver early Fibrosis is the key to the treatment of chronic liver disease. At this forum, domestic and foreign experts reached a consensus: all kinds of patients with chronic liver disease should choose anti-fibrotic treatment as soon as possible after receiving anti-viral treatment, so as to obtain more active and effective treatment guarantee and even obtain Hope for recovery.
FibroScan is a new type of liver fibrosis in vitro testing equipment invented and produced by France ECHOSENS. It is also the only non-invasive real-time testing device in the world to diagnose and monitor chronic liver disease by quantifying liver hardness values. It is simple to use and can accurately judge the degree of liver fibrosis of chronic liver diseases caused by various causes. Compared with the traditional liver puncture test, it has the advantages of accurate classification, no trauma and pain, and can greatly reduce the cost of patient examination. Currently, this device is used in many countries and regions.
According to Prof. Jia Jidong from Beijing Friendship Hospital, the “FibroScan China Multi-Center Clinical Validation of Hepatitis B Patients†study was conducted to verify the effectiveness of FibroScan in detecting chronic hepatitis B liver fibrosis. It was launched in September 2007 and is affiliated to Beijing You’an Hospital of Capital Medical University. Beijing Friendship Hospital affiliated to Capital Medical University, 302 Hospital of Chinese People's Liberation Army, Southern Hospital of Southern Medical University, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Chongqing Southwest Hospital of Third Military Medical University, Renji Hospital of Shanghai Jiaotong University School of Medicine Seven national medical centers have conducted open and forward-looking research. The results showed that FibroScan detection showed significant differences in liver stiffness between patients with different liver fibrosis, and was closely related to the degree of liver fibrosis; it can accurately detect the degree of liver fibrosis, and the higher the degree of liver fibrosis, the higher the accuracy.
According to Professor Hou Jinlin, Department of Infectious Medicine, Southern Hospital of Southern Medical University, FibroScan diagnosed liver fibrosis with a sensitivity of 70% and a specificity of 84%. Diagnosis of cirrhosis with a sensitivity of 87% and a specificity of 91%. FibroScan diagnosis of liver fibrosis can prevent liver biopsy in more than 75% of patients. These results indicate that FibroScan has a high degree of accuracy in the grading diagnosis of various stages of liver fibrosis.
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