Do not enter the broiler chicks with good reputation, no chicken or white pheasant bred into the breeder farm, and strictly control the quality of chicks. Practice has shown that feeding newborn chickens without bacteria is the best way to prevent this disease. Pay attention to environmental disinfection and improve the disinfection facilities in the field. The environment of the chicken farm should be disinfected once a week with 10%~25% lime water or 3% caustic soda water; the brooding room must be completely cleaned, brushed or disinfected before entering the brood. Strengthen day-to-day management to ensure that the chicken house temperature and chick density are reasonable, and chicks found to have suspicious symptoms should be promptly chopped up and kept in isolation. If the rearing of breeder chickens is to be resolutely eliminated, if the commercial chickens are to be treated with drugs in a timely manner, the cured chickens will still have to be reared separately, otherwise it will become a new source of infection.